How importance of desexing your dog. If I choose to mate my female dog, when should that be done?

We have talked about how importance of desexing your dog.  If I choose to mate my female dog, when should that be done? 

If you plan to mate your dog, she should have at least one or two heat periods first. This will allow her to physically mature allowing her to be a better mother without such a physical drain on her. We do not recommend breeding after 5 years of age unless she has been bred from prior to that. Having her first litter after 5 years of age increases the risk of problems during the pregnancy and/or delivery. Once your dog has had her last litter, it is worth considering spaying in order to prevent uterine infections and other reproductive problems.

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